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Brain complexity and damage in patients with multiple sclerosis using fractal analysis
A new imaging outcome for monitoring MS severity
Development of imaging markers of disease severity for MS is a high priority. We have previously described that the analysis of the Fractal Dimension (FD) of the brain is significantly altered in MS patients and its subtypes. The aim of this work is twofold. Firstly to assess the accuracy of Fractal Analysis when classifying MS patients against controls and based in disease severity. Secondly, to assess whether FD can predict the time to disability progression.